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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INCENP All Species: 9.7
Human Site: S291 Identified Species: 23.7
UniProt: Q9NQS7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQS7 NP_001035784.1 918 105429 S291 P I L P D N F S T P T G S R T
Chimpanzee Pan troglodytes XP_001151716 913 104783 S291 P I L P D N F S T P T G S H M
Rhesus Macaque Macaca mulatta XP_001118481 897 102420 S291 P I L P N N F S M P T G S P A
Dog Lupus familis XP_853705 896 101812 Q296 P T G T H V D Q Q S V W H S L
Cat Felis silvestris
Mouse Mus musculus Q9WU62 880 101190 L267 P I L L N N I L P T T A K S P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519483 997 113500 V333 K A A R E S A V A N R V V C R
Chicken Gallus gallus P53352 877 100922 S341 A P Q K L S V S S S S V N G S
Frog Xenopus laevis O13024 873 101180 I333 I E M V D D E I T I K I R P E
Zebra Danio Brachydanio rerio XP_002666634 833 95304 T333 E E K E I E L T E E K L P E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMA7 1430 159034 Q542 R L L E E A E Q Q K R L Q E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 92.9 79.4 N.A. 72.3 N.A. N.A. 47.3 46.6 47 30.1 N.A. 20.9 N.A. N.A. N.A.
Protein Similarity: 100 99.1 94.7 85.4 N.A. 82 N.A. N.A. 62.7 63.5 63.7 49.2 N.A. 36.3 N.A. N.A. N.A.
P-Site Identity: 100 86.6 73.3 6.6 N.A. 33.3 N.A. N.A. 0 6.6 13.3 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 80 6.6 N.A. 40 N.A. N.A. 13.3 40 26.6 6.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 10 10 0 10 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 30 10 10 0 0 0 0 0 0 0 0 % D
% Glu: 10 20 0 20 20 10 20 0 10 10 0 0 0 20 20 % E
% Phe: 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 30 0 10 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 10 10 0 % H
% Ile: 10 40 0 0 10 0 10 10 0 10 0 10 0 0 0 % I
% Lys: 10 0 10 10 0 0 0 0 0 10 20 0 10 0 0 % K
% Leu: 0 10 50 10 10 0 10 10 0 0 0 20 0 0 10 % L
% Met: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 20 40 0 0 0 10 0 0 10 0 0 % N
% Pro: 50 10 0 30 0 0 0 0 10 30 0 0 10 20 10 % P
% Gln: 0 0 10 0 0 0 0 20 20 0 0 0 10 0 0 % Q
% Arg: 10 0 0 10 0 0 0 0 0 0 20 0 10 10 10 % R
% Ser: 0 0 0 0 0 20 0 40 10 20 10 0 30 20 10 % S
% Thr: 0 10 0 10 0 0 0 10 30 10 40 0 0 0 10 % T
% Val: 0 0 0 10 0 10 10 10 0 0 10 20 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _